Controlled Release
In hydrophilic matrix systems, Cellulose ether is uniformly incorporated throughout the tablet. Upon contact with water, the outer tablet skin is partially hydrated, forming a gel layer. The rate of diffusion of actives out of the gel layer and the rate of erosion determine the overall tablet dissolution and drug delivery rates. Precise and reliable adjustments of these rates are possible because the properties of cellulose ethers have been so well documented.